Floyd Chilton

Professor, Nutritional Sciences

Member of the Graduate Faculty

Professor, BIO5 Institute

Professor, Cancer Biology - GIDP

Professor, Innovations in Aging - GIDP

Dr. Chilton is passionate about providing solutions to overcome physical and emotional suffering so that people can live better, more joyful lives. He is a successful innovator in a wide range of areas including an academic professor (with over 140 scientific publications), an entrepreneur (starting several companies and one non-profit organization), and an inventor (holding over 25 patents). Dr. Chilton is widely recognized in academia and industry for his work on nutrition in the context of variation in the human genome and has been a pioneer in the areas of personalized or precision nutrition and wellness. Dr. Chilton has over 30 years of continuous funding from the National Institutes of Health. Currently he serves as a Professor of Nutritional Sciences, Associate Director of the BIO5 Institute, and Director of the Precision Nutrition and Wellness Initiative at the University of Arizona. Specifically, Dr. Chilton’s work examines how genetic and epigenetic variations interact with human diets (especially the modern Western diet) to drive inflammation and inflammatory disorders (including cardiovascular disease and cancer), as well as psychiatric/developmental disorders (ADHD, autism spectrum disorder, and depression). These precision-, individualized- and population-based research approaches provide a wide range of opportunities to benefit humans that include: 1) providing a long-sought pathogenetic mechanism that underscores the different biologic behavior of inflammatory diseases in different racial/ethnic populations; 2) discovering new biomarkers of disease aggressiveness for early diagnostic and therapeutic intervention; 3) revealing new therapeutic strategies to affect disease aggressiveness using precision gene-based dietary, wellness and/or pharmacologic interventions; and 4) creating therapeutic foods and supplements that optimize immune system and brain development for different populations around the world. Dr. Chilton has won numerous awards for this work, including the Alumni Achievement Award at Western Carolina University, the Denham Harmon Outstanding Research Achievement Award from the American College for Advancement of Medicine and the 2016 Established Investigator Award at Wake Forest School of Medicine. Currently, his laboratory focuses on precision health as it relates to genetic variations associated with polyunsaturated fatty acid (PUFA) biosynthesis and metabolism and how gene-diet interactions impact molecular and clinical phenotypes associated with human health. Specifically, his work addresses the role of gene-diet interactions in driving inflammation and inflammatory disorders (including cardiovascular disease and cancer) as well as psychiatric/developmental disorders (ADHD, autism spectrum disorder and depression). His lab also examines how gene-diet interactions caused by the modern Western diet lead to marked changes (excesses and deficiencies) in PUFA levels and signaling in circulation, cells and tissues and how specific human nutrition supplementation strategies can be used to normalize these changes. In addition to his research, Dr. Chilton has also had the opportunity to touch hundreds of thousands of lives as an author of five lay books focused on nutrition, diet, and physical and mental health. These books include Inflammation Nation (Simon and Schuster), Win the War Within (Rodale), The Gene Smart Diet (Rodale) and Made to Crave Action Plan (Zondervan). His most recent book, The Rewired Brain addresses the issue of the unconscious mind, its capacity to negatively impact our lives, and how thought patterns induce genetic (epigenetic) changes that alter brain circuitry. This gives humans the capacity to rewire and change their minds and thus their lives.

Offering Research Opportunities?


Prerequisite Courses


Majors Considered

Nutritional Sciences Physiology

Types of Opportunities

Description of Opportunity

No description given

Start Date

January 2020

Primary Department

Affiliated Departments

Research Location